Overview: The epidermis is the outermost layer of the skin, primarily composed of keratinocytes. Its primary function is to act as a barrier between the body and the external environment.
Functions:
- Protection: The epidermis protects against environmental factors such as pathogens (bacteria, viruses), chemicals, and physical abrasions. The outermost layer, the stratum corneum, is particularly important as it consists of dead, keratinized cells that provide a tough barrier.
- Water Regulation: The epidermis helps to prevent water loss from the body, maintaining hydration levels. It does this through a process called transepidermal water loss (TEWL), where moisture is retained within the skin.
- Sensation: Specialized cells within the epidermis, such as Merkel cells, are responsible for the sensation of touch. These cells connect to nerve endings, allowing the skin to detect tactile stimuli.
- Immune Response: The epidermis contains Langerhans cells that play a crucial role in the immune system by identifying and fighting off foreign invaders.